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Czech Gynaecological and Obstetrical Society | Ministry of Health | Faculty of Medicine, Masaryk University |       Institute of Biostatistics and Analyses, Masaryk University
GlaxoSmithKline     Roche |

Other sources of information
Cervical cytology (in Czech)www.cipek.cz
Cervical cytology
Cancer Screening in the European Unionec.europa.eu
Cancer Screening in the European Union (2017)
[ 10,6 MB]
SVOD - Epidemiology of malignant tumours in the Czech Republicwww.svod.cz
Epidemiology of malignant tumours
in the Czech Republic
NCI Bethesda System
HPV College


Screening process

1. Examination by the registering gynaecologist

  1. The woman is examined by her registering gynaecologist during her regular preventive checkup. Cervical smear test is part of this examination.
  2. The gynaecologist sends the cervical smear together with the accompanying form to an accredited cytology laboratory.
  3. The accredited cytology laboratory then performs a standard examination of the sample, according to defined methods. The result of the examination (according to the standard classification Bethesda 2001) is sent back to the registering gynaecologist; this must be done not later than 3 weeks after the day of cervical smear test.
  4. Based on the results of cytological examination, the registering gynaecologist decides on what to do next.

2. Negative result

  • In case of negative result of cervical smear test, the client is recommended to attend another screening examination within a preventive checkup after one year (see Figure 1).

Figure 1: Scheme of cytological examination. The registering gynaecologist sends a sample of cervical smear to the accredited cytology laboratory, and gets back the result within three weeks. In case of negative result, the client is recommended to attend another preventive checkup after one year.

3. Repeated smear

In case of other than negative result of cervical smear test, the registering gynaecologist is obliged to send repeated smear or histology result to the laboratory within a defined time period, depending on the seriousness of the first cervical smear result. If the gynaecologist fails to do so, the laboratory inquires of him.

The following table summarizes time periods after which the laboratory inquires* of the gynaecologist, depending on smear test result:

Smear test result
Inquiry* after ...
Normal ---
Inadequate smear 4 months
ACS-US 7 months
ASC-H 4 months
LSIL 7 months
HSIL 4 months
HSIL - invasion cannot be excluded 4 months
Squamous cell carcinoma 4 months
AGC-NOS 4 months
AGC-NEO 4 months
Adenocarcinoma in situ - AIS 4 months
Invasive adenocarcinoma 4 months
Other malignant tumours 4 months
Other Facultatively

*Only if the gynaecologist fails to send repeated smear or histology result to the laboratory.

The result of histopathological examination is sent back to the centre which requested this examination. The registering gynaecologist must also be informed about the result. If results of the histopathological examination are not delivered in time, the gynaecologist is obliged to inquire himself and to report this failure to the Cervical Cancer Screening Committee at the Ministry of Health. Based on the result of histopathological examination, the gynaecologist decides on possible treatment of the patient.

The gynaecologist then sends his report to the accredited cytology laboratory, which subsequently enters these data into the database.

Figure 2: Schematic representation of follow-up of any patient in which other than negative smear test result was found.


Last updated on 7 January 2014